Genetic predisposition and stress-induced hypertension

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Science  09 Jul 1976:
Vol. 193, Issue 4248, pp. 161-162
DOI: 10.1126/science.945610


When chronically exposed to an approach-avoidance conflict, rats with a genetic susceptibility to hypertension showed persisten elevations in systolic blood pressure, but rats with a genetic resistance to hypertension did not. Hence, psychic stress is selectively efficacious in producing hypertensive effects depending on genetic predisposition of the animal.