A human syndrome caused by immotile cilia

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Science  23 Jul 1976:
Vol. 193, Issue 4250, pp. 317-319
DOI: 10.1126/science.1084576


Four subjects who produced immotile sperm were studied. In three of the subjects, who had frequent bronchitis and sinusitis, there was no mucociliary transport, as measured by tracheobronchial clearance. Electron microscopy indicated that cilia from cells of these patients lack dynein arms.

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