Vertebrate central nervous system: same neurons mediate both electrical and chemical inhibitions

See allHide authors and affiliations

Science  10 Dec 1976:
Vol. 194, Issue 4270, pp. 1166-1169
DOI: 10.1126/science.186868


Identified goldfish medullary interneurons previously shown to inhibit the Mauthner cell electrically also produce a classical postsynaptic inhibition of that cell. Failure of active spike propagation in the processes of these interneurons underlies generation of the electrical component, and the resultant electrotonic terminal depolarization is sufficient to evoke inhibitory transmitter release.