Asymptomatic gonorrhea in men: caused by gonococci with unique nutritional requirements

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Science  17 Jun 1977:
Vol. 196, Issue 4296, pp. 1352-1353
DOI: 10.1126/science.405742


In a retrospective case-control study, gonococci with nutritional requirements for arginine, hypoxanthine, and uracil were recovered from 24 of 25 men with asymptomatic gonorrhea and 10 of 25 men with symptomatic gonorrhea (P = .0001). These strains represent a smaller proportion of gonococcal isolate from blacks than from whites. Asymptomatic urethral infection is important in the epidemiology of gonorrhea, particularly among whites.