Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs

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Science  09 Sep 1977:
Vol. 197, Issue 4308, pp. 1092-1094
DOI: 10.1126/science.887941


Three-month-old rats were injected intraperitoneally with [3H]thymidine (4.3 microcuries per gram of body weight) and allowed to survive for 30 days. Radioautography of 1-micrometer sections revealed labeled cells in the granular layers of dentate gyrus and olfactory bulb; these were confirmed as neurons by electron microscopy of reembedded 1-micrometer sections.

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