Memory formation: evidence for a specific neurochemical system in the amygdala

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Science  28 Oct 1977:
Vol. 198, Issue 4315, pp. 423-425
DOI: 10.1126/science.20664


beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic antagonists were both stereospecific and reversed by norepinephrine. The results support a role for an amygdala beta-adrenergic system in memory processes.

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