Phototoxic keratoconjunctivitis from coal-tar pitch volatiles

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Science  25 Nov 1977:
Vol. 198, Issue 4319, pp. 841-842
DOI: 10.1126/science.918667


Roofers working with coal-tar pitch develop burning eyes and conjunctivitis which they subjectively associate with sun exposure. A coal-tar pitch distillate instilled in the conjunctivae of rabbits produced minimal or mild irritation in the absence of ultraviolet radiation, but irradiation with long-ultraviolet produced marked photophobia and severe keratoconjunctivitis.