Melatonin Content of the Human Pineal Gland

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Science  06 Jan 1978:
Vol. 199, Issue 4324, pp. 83-84
DOI: 10.1126/science.199.4324.83


Gas chromatography with electron capture detection was used to quantitate melatonin in single human pineal glands. The sensitivity of this melatonin assay is in the low picogram range. A 24-hour rhythm of pineal melatonin content was observed.