Fertilization-induced changes in membrane fluidity of sea urchin eggs

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Science  24 Mar 1978:
Vol. 199, Issue 4335, pp. 1336-1337
DOI: 10.1126/science.564549


By use of a spin label fatty acid, 5-doxylstearate, an increase in bulk membrane fluidity was observed after fertilization of two species of sea urchin eggs. Eggs partially activated by ammonia showed a similar effect. The data suggest that a structural change involving membrane lipids accompanies activation.