Implications of RNA-RNA splicing in evolution of eukaryotic cells

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Science  22 Dec 1978:
Vol. 202, Issue 4374, pp. 1257-1260
DOI: 10.1126/science.364651


The differences in the biochemistry of messenger RNA formation in eukaryotes compared to prokaryotes are so profound as to suggest that sequential prokaryotic to eukaryotic cell evolution seems unlikely. The recently discovered noncontiguous sequences in eukaryotic DNA that encode messenger RNA may reflect an ancient, rather than a new, distribution of information in DNA and that eukaryotes evolved independently of prokaryotes.