Nicotinamide adenine dinucleotide splitting enzyme: a characteristic of the mouse macrophage

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Science  22 Dec 1978:
Vol. 202, Issue 4374, pp. 1293-1295
DOI: 10.1126/science.214853


Murine macrophages are endowed with nicotinamide adenine dinucleotide splitting activity that is markedly higher than that of other cells, tissues, or organs of the mouse. This enzyme therefore can be used as a biochemical marker for distinguishing macrophages from other cells of the lymphoreticular system and from polymorphonuclear leukocytes.