Molecular Analysis by Mass Spectrometry

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Science  13 Jul 1979:
Vol. 205, Issue 4402, pp. 151-159
DOI: 10.1126/science.205.4402.151

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New ionization methods combined with powerful analyzers, detectors, and data systems have made mass spectrometry a versatile tool for molecular analysis. Samples consisting of nanogram quantities of hundreds of unique components are routinely analyzed. In favorable cases samples as small as 2.5 x 10–14 gram and samples with masses of more than 3000 atomic mass units have been successfully examined.