Myosin heads do not move on activation in highly stretched vertebrate striated muscle

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Science  18 Jan 1980:
Vol. 207, Issue 4428, pp. 307-308
DOI: 10.1126/science.6444254


Highly stretched muscles in which thick and thin filaments no longer overlap produce little or no tension on activation. In preparations producing no tension, the 42.9-nanometer myosin layer line shown in x-ray diffraction patterns does not become weaker. This suggests that myosin heads do not move from their resting positions in the absence of actin.