Tooth induction in chick epithelium: expression of quiescent genes for enamel synthesis

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Science  29 Feb 1980:
Vol. 207, Issue 4434, pp. 993-995
DOI: 10.1126/science.7352302


Intraocular grafts of chick epithelium combined with mouse molar mesenchyme produced a variety of dental structures including perfectly formed crowns with differentiated ameloblasts depositing enamel matrix. The results suggest that the loss of teeth in Aves did not result from a loss of genetic coding for enamel synthesis in the oral epithelium but from an alteration in the tissue interactions requisite for odontogenesis.

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