Glutamine- and N-acetylglutamate-dependent carbamoyl phosphate synthetase in elasmobranchs

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Science  18 Apr 1980:
Vol. 208, Issue 4441, pp. 291-293
DOI: 10.1126/science.6245445


High levels of glutamine- and N-acetyl-L-glutamate-dependent carbamoyl phosphate synthetase activity are present in liver extracts of marine species of fish that retain high levels of urea in their tissues for the purpose of osmoregulation. The function of the synthetase in these species appears to be related to urea synthesis.

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