Ion Pairing Techniques: Compatibility with On-Line Liquid Chromatography—Mass Spectrometry

See allHide authors and affiliations

Science  25 Jul 1980:
Vol. 209, Issue 4455, pp. 495-497
DOI: 10.1126/science.209.4455.495


The mass spectrometric properties of a series of model ion pairs were examined. In the cases studied it was possible to vaporize the ion pair consituents and to produce spectra corresponding to those of the unpaired materials. These findings offer a convenient means for derivatizing certain ionic compounds and demonstrate the feasibility of analyzing ionic species by on-line liquid chromatography-mass spectrometry.