Swelling of nerve fibers associated with action potentials

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Science  17 Oct 1980:
Vol. 210, Issue 4467, pp. 338-339
DOI: 10.1126/science.7423196


Swelling of nerve fibers during the action potential was demonstrated by three different methods. Generation of a propagated nerve impulse in a crab nerve produced an outward movement of 50 to 100 angstroms of the nerve surfce and a rise in swelling pressure on the order of 5 dynes per square centimeter. In squid giant axons, the amplitude of the observed outward movement of the surface was small.

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