Fourier-transformed infrared photoacoustic spectroscopy of biological materials

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Science  21 Nov 1980:
Vol. 210, Issue 4472, pp. 918-920
DOI: 10.1126/science.7434007


A new technique for measuring the infrared spectra of solids has been developed. The photoacoustic spectra of hemin, hemoglobin, protoporphyrin IX, and horseradish peroxidase show how this technique can be used to obtain structural information about biological materials which cannot readily be studied by normal transmission infrared spectroscopy. The method requires milligram quantities of material and involves no sample preparation.