Optical recording of calcium action potentials from growth cones of cultured neurons with a laser microbeam

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Science  05 Jun 1981:
Vol. 212, Issue 4499, pp. 1164-1167
DOI: 10.1126/science.7233210


Simultaneous recordings of calcium action potentials directly from growth cones and from somata of neuroblastoma cells indicated that they could be generated in the neurites at or near growth cones. Growth cone responses were measured with a fluorescent voltage-sensitive dye and a 5-milliwatt helium-neon laser microbeam as a monitoring light source.

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