Pentapeptide (proctolin) associated with an identified neuron

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Science  31 Jul 1981:
Vol. 213, Issue 4507, pp. 567-569
DOI: 10.1126/science.6113690


Individual neurons can be recognized and identified anatomically, physiologically, and biochemically in the insect central nervous system. Biochemical analyses of extracts prepared from one such identified neuron show it to be associated with a bioactive pentapeptide called proctolin. This peptide may be a neurotransmitter, and a preparation is established in which its physiological action can be studied at the cellular level.

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