Cardiac sarcolemma: compositional adaptation to exercise

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Science  11 Sep 1981:
Vol. 213, Issue 4513, pp. 1271-1273
DOI: 10.1126/science.7268437


Marked changes were observed in the lipid composition of highly purified plasma membranes isolated from the hearts of rats subjected to daily treadmill running. Compared to sedentary controls, sarcolemmal content of total phospholipid and phosphatidylserine in the trained group was increased 23 and 50 percent, respectively. This observation suggests a mechanism by which cardiac contractility may be enhanced by exercise.