X-linked ichthyosis: increased blood cholesterol sulfate and electrophoretic mobility of low-density lipoprotein

See allHide authors and affiliations

Science  06 Nov 1981:
Vol. 214, Issue 4521, pp. 659-660
DOI: 10.1126/science.6945674


Plasma cholesterol sulfate concentration is increased in patients with recessive X-linked ichthyosis, a disease in which steroid sulfatase activity is absent. In these patients, cholesterol sulfate is found primarily in the low-density lipoprotein fraction of plasma, and the electrophoretic mobility of these lipoproteins is greatly increased.

Stay Connected to Science