Neurons in the rat dentate gyrus granular layer substantially increase during juvenile and adult life

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Science  21 May 1982:
Vol. 216, Issue 4548, pp. 890-892
DOI: 10.1126/science.7079742


Volumetric estimates of the total number of granule cells in rats 30, 120, 200, and 365 days old increase linearly by approximately 35 to 43 percent between 1 month and 1 year. Total volume of the granular layer also grows linearly during that time. These results demonstrate a numerical increase in a neuronal population during adulthood in the mammalian brain.

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