Sexual dimorphism in the human corpus callosum

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Science  25 Jun 1982:
Vol. 216, Issue 4553, pp. 1431-1432
DOI: 10.1126/science.7089533


Preliminary observations suggest a sex difference in the shape and surface area of the human corpus callosum. The sexual dimorphism is striking in the splenium, the caudal or posterior portion of the corpus callosum. The female splenium is both more bulbous and larger than the male counterpart. Since peristriate, parietal, and superior temporal fibers course through the splenium, this finding could be related to possible gender differences in the degree of lateralization for visuospatial functions.

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