Potassium currents in Drosophila: different components affected by mutations of two genes

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Science  03 Jun 1983:
Vol. 220, Issue 4601, pp. 1076-1078
DOI: 10.1126/science.6302847


Electrophysiological analysis of the Drosophila behavioral mutants Eag and Sh and the double mutant Eag Sh indicates that the products of both genes take part in the control of potassium currents in the membranes of both nerve and muscle. In voltage-clamped larval muscle fibers, Sh affects the transient A current, whereas Eag reduces the delayed rectification and, to a lesser extent, the A current.

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