Induction of neuronal branching in Caenorhabditis elegans

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Science  01 Jul 1983:
Vol. 221, Issue 4605, pp. 61-63
DOI: 10.1126/science.6857263


The two postembryonic touch receptor neurons in the nematode Caenorhabditis elegans arise from essentially identical cell lineages and have the same ultrastructural features. The cells are found in different positions in the animal, however, and differ in neuronal branching, connectivity, and function. These structural and functional differences are not seen when cells are placed in similar positions by mutation or laser-induced damage. Thus, some, but probably not all, of the differentiated properties of these cells are a consequence of their cellular environment.

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