Inhibition of tumor promotion by a biomimetic superoxide dismutase

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Science  01 Jul 1983:
Vol. 221, Issue 4605, pp. 75-77
DOI: 10.1126/science.6857269


A low molecular weight, lipophilic, copper coordination complex with superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.

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