5-hydroxytryptophan elevates serum melatonin

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Science  12 Aug 1983:
Vol. 221, Issue 4611, pp. 659-661
DOI: 10.1126/science.6867734


Daytime administration of 5-hydroxytryptophan to sheep elevated serum melatonin more than sevenfold within 2 hours. This suggests that administration of 5-hydroxytryptophan could be used as the basis of a clinical test of pineal function and that melatonin might mediate some clinical effects of 5-hydroxytryptophan.