Spectrographic representation of globular protein breathing motions

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Science  13 Jan 1984:
Vol. 223, Issue 4632, pp. 181-182
DOI: 10.1126/science.6691144


Two useful ways of describing the frequency composition of the breathing motions of globular proteins are the spectrogram and three-dimensional power spectrum, representations similar to those frequently used in speech analysis. In this report "low-frequency" vibrations of globular proteins, corresponding to the collective oscillations of atoms from many different residues, are considered. Radii of gyration fluctuations provide a sensitive way to characterize such concerted motions.

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