Human chorionic gonadotropin secreted by preimplantation embryos cultured in vitro

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Science  24 Feb 1984:
Vol. 223, Issue 4638, pp. 816-818
DOI: 10.1126/science.6546453


Human oocytes were collected by laparoscopy and fertilized and cultured in vitro. Human chorionic gonadotropin was detected in the medium surrounding two embryos cultured for more than 7 days after fertilization.