Simian AIDS: isolation of a type D retrovirus and transmission of the disease

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Science  09 Mar 1984:
Vol. 223, Issue 4640, pp. 1083-1086
DOI: 10.1126/science.6695196


A type D retrovirus related to but distinct from Mason-Pfizer monkey virus was isolated in vitro from the blood of two rhesus monkeys (Macaca mulatta) with simian acquired immunodeficiency syndrome (SAIDS). Three juvenile rhesus monkeys that were injected intravenously with tissue culture fluids containing this virus developed SAIDS after 2 to 4 weeks.