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Cell sensitivity to gravity

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Science  13 Jul 1984:
Vol. 225, Issue 4658, pp. 228-230
DOI: 10.1126/science.6729481

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Cultures of human lymphocytes exposed in microgravity to the mitogen concanavalin A showed less than 3 percent of the activation of ground controls. This result supports the hypothesis, based on simulations at low g and experiments at high g, that microgravity depresses whereas high gravity enhances cell proliferation rates. The effects of gravity are particularly strong in cells undergoing differentiation.