A trans-acting product needed for P factor transposition in Drosophila

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Science  07 Dec 1984:
Vol. 226, Issue 4679, pp. 1194-1196
DOI: 10.1126/science.6095450


A transposable genetic element of the P family in Drosophila melanogaster was found to be unstable in the presence of other P elements but stable in their absence. A sensitive assay for P transpositional activity is provided by the snw allele, a defective P insert in the singed bristle locus which becomes hypermutable only in the presence of complete elements. This measure of activity was highly correlated with a type of female sterility normally associated with P activity. There was no cross-reactivity with transposase from another hybrid dysgenesis-causing element (the I factor).

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