Interactions between the gonadal steroids and the immune system

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Science  18 Jan 1985:
Vol. 227, Issue 4684, pp. 257-261
DOI: 10.1126/science.3871252


The immune system is regulated by the gonadal steroids estrogen, androgen, and progesterone, but the circulating levels of these steroids can also be affected by immune system function. Such interactions appear to be mediated through the hypothalamic-pituitary-gonadal-thymic axis and depend on pituitary luteinizing hormone released by thymic factors under the control of the gonadal steroids.

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