Wounding and its role in RSV-mediated tumor formation

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Science  08 Nov 1985:
Vol. 230, Issue 4726, pp. 676-678
DOI: 10.1126/science.2996144


Tumors induced in chickens by Rous sarcoma virus remain localized at the site of injection even though the animals become viremic. Tumors have now been shown to be inducible at other sites if a wound is inflicted or if the tissue is injured by administration of tumor promoters. These findings indicate that local wounding plays a role in the spread of tumorigenicity of Rous sarcoma virus.

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