Sevenless: A Cell-Specific Homeotic Mutation of the Drosophila Eye

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Science  24 Jan 1986:
Vol. 231, Issue 4736, pp. 400-402
DOI: 10.1126/science.231.4736.400


Each ommatidium in the compound eye of the Drosophila mutant sevenless lacks photoreceptor number seven (R7) from the normal ommatidial complement of eight photoreceptors. A comparison of mutant and normal development reveals that this deficit is caused by the cell-specific transformation of the cell normally fated to produce R7 into a lens-secreting accessory cell, a cone cell.

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