Cerebellar vermis: essential for long-term habituation of the acoustic startle response

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Science  25 Apr 1986:
Vol. 232, Issue 4749, pp. 513-515
DOI: 10.1126/science.3961494


The acoustic startle response in rats shows both short-term habituation, which recovers in seconds or minutes, and long-term habituation, which is effectively permanent. Lesions of the cerebellar vermis significantly attenuated long-term habituation without affecting the short-term process or altering initial response levels. In this response system the cerebellar vermis is part of an essential circuit for long-term habituation.

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