10 May 1991
Vol 252, Issue 5007

About The Cover

Crystal structure of a zinc finger—DNA complex from the mouse protein Zif268. The view is down the axis of the double-helical DNA and emphasizes the symmetry of the complex. The DNA is blue; individual zinc finger domains are red, yellow, and purple; and zinc atoms are light blue. Similar DNA-binding domains occur in a large family of eukaryotic regulatory proteins. See page 809. [Photograph by N. P. Pavletich and C. O. Pabo]