Chromosome size-dependent control of meiotic recombination

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Science  10 Apr 1992:
Vol. 256, Issue 5054, pp. 228-232
DOI: 10.1126/science.1566070


Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

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