Occurrence of sialic acids in Drosophila melanogaster

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Science  01 May 1992:
Vol. 256, Issue 5057, pp. 673-675
DOI: 10.1126/science.1585182


Sialylated oligosaccharides, which are cell type-specific and developmentally regulated, have been implicated in a variety of complex biological events. Their broad functional importance is reflected by their presence in a wide variety of phyla extending from Echinodermata through higher vertebrates. Here, sialic acids are detected throughout development in an insect, Drosophila. Homopolymers of alpha 2,8-linked sialic acid, polysialic acid, are developmentally regulated and only expressed during early Drosophila development.

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