04 February 1994
Vol 263, Issue 5147

About The Cover

A platinum replica revealing the cytoplasmic face of a phagosome containing a mycobacterium. The phagosome was isolated from a bone marrow-derived murine macrophage, fixed in glutaraldehyde, and frozen on a liquid helium-cooled copper block before freeze-drying and rotary replication. The photomicrograph was scanned and colorized with Adobe Photoshop. See page 678 and the Perspective on page 637. [Photomicrograph: David G. Russell]