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Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

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Science  03 Nov 1995:
Vol. 270, Issue 5237, pp. 797-800
DOI: 10.1126/science.270.5237.797

Article Information

vol. 270 no. 5237 797-800

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Author Information

  1. Sarah M. Russell,
  2. Nahid Tayebi(1),
  3. Hiroshi Nakajima(1),
  4. Mary C. Riedy(2),
  5. Joseph L. Roberts(2),
  6. M. Javad Aman(2),
  7. Thi-Sau Migone,
  8. Masayuki Noguchi,
  9. M. Louise Markert,
  10. Rebecca H. Buckley,
  11. John J. O'Shea,
  12. Warren J. Leonard(3)
  1. S. M. Russell, H. Nakajima, M. J. Aman, T.-S. Migone, M. Noguchi, W. J. Leonard, Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  2. N. Tayebi, Unit on Clinical Genetics, Clinical Neuroscience Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
  3. M. C. Riedy and J. J. O'Shea, Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD 20892, USA.
  4. J. L. Roberts, Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA.
  5. M. L. Markert and R. H. Buckley, Departments of Immunology and Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA.
  1. (1) These authors contributed equally to this work.
  2. (2) These authors contributed equally to this work.
  3. (3) To whom correspondence should be addressed at Laboratory of Molecular Immunology, NHLBI, NIH, Building 10, Room 7N244, Bethesda, MD 20892-1674, USA.

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