Chromosomal Control of Meiotic Cell Division

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Science  08 Dec 1995:
Vol. 270, Issue 5242, pp. 1595-1601
DOI: 10.1126/science.270.5242.1595


Chromosomes have multiple roles both in controlling the cell assembly and structure of the spindle and in determining chromosomal position on the spindle in many meiotic cells and in some types of mitotic cells. Moreover, functionally significant chromosome-microtubule interactions are not limited to the kinetochore but are also mediated by proteins localized along the arms of chromosomes. Finally, chromosomes also play a crucial role in control of the cell cycle.

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