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Amelioration of Vascular Dysfunctions in Diabetic Rats by an Oral PKC β Inhibitor
- Hidehiro Ishii,
- Michael R. Jirousek,
- Daisuke Koya,
- Chikako Takagi,
- Pu Xia,
- Allen Clermont,
- Sven-Erik Bursell,
- Timothy S. Kern,
- Lawrence M. Ballas,
- William F. Heath,
- Lawrence E. Stramm,
- Edward P. Feener,
- George L. King*
- H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
- M. R. Jirousek, W. F. Heath, L. E. Stramm, Lilly Laboratories, Indianapolis, IN 46285, USA.
- T. S. Kern, Department of Ophthalmology, University of Wisconsin, Madison, WI 53706, USA.
- L. M. Ballas, Sphinx Pharmaceutical, Durham, NC 27707, USA.
- ↵* To whom correspondence should be addressed.
See allHide authors and affiliations
Science 03 May 1996:
Vol. 272, Issue 5262, pp. 728-731
DOI: 10.1126/science.272.5262.728
Vol. 272, Issue 5262, pp. 728-731
DOI: 10.1126/science.272.5262.728
Hidehiro Ishii
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Michael R. Jirousek
M. R. Jirousek, W. F. Heath, L. E. Stramm, Lilly Laboratories, Indianapolis, IN 46285, USA.
Daisuke Koya
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Chikako Takagi
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Pu Xia
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Allen Clermont
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Sven-Erik Bursell
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
Timothy S. Kern
T. S. Kern, Department of Ophthalmology, University of Wisconsin, Madison, WI 53706, USA.
Lawrence M. Ballas
L. M. Ballas, Sphinx Pharmaceutical, Durham, NC 27707, USA.
William F. Heath
M. R. Jirousek, W. F. Heath, L. E. Stramm, Lilly Laboratories, Indianapolis, IN 46285, USA.
Lawrence E. Stramm
M. R. Jirousek, W. F. Heath, L. E. Stramm, Lilly Laboratories, Indianapolis, IN 46285, USA.
Edward P. Feener
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
George L. King
H. Ishii, D. Koya, C. Takagi, P. Xia, A. Clermont, S.-E. Bursell, E. P. Feener, G. L. King, Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.
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