A Perspective on AIDS Vaccines

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Science  28 Jun 1996:
Vol. 272, Issue 5270, pp. 1888
DOI: 10.1126/science.272.5270.1888


To many people it is unfathomable that after more than 10 years of research, there is no human immunodeficiency virus (HIV) vaccine ready for large-scale efficacy trials. A complex web of scientific, political, and social issues remains to be untangled. Barry Bloom (Howard Hughes Medical Institute, Albert Einstein College of Medicine, USA) takes a hard look at the fundamental questions that must be answered before a vaccine against acquired immunodeficiency syndrome (AIDS) becomes a reality.