Rho Return--Its Targets in Focal Adhesions

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Science  12 Jul 1996:
Vol. 273, Issue 5272, pp. 203
DOI: 10.1126/science.273.5272.203


Rho, a small molecular weight guanosine triphosphate binding protein, is a morphogenetic coordinator in yeast and mammalian cells. A paper in this week's issue by Kimura et al. (p. 245) reveals the biochemical details of how Rho activates myosin in stress fibers. In his Perspective, Bussey points out the similarities of the new information to morphogenetic systems in yeast.