Life with 6000 Genes

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Science  25 Oct 1996:
Vol. 274, Issue 5287, pp. 546-567
DOI: 10.1126/science.274.5287.546


  • Table 1.

    Finding yeast genome information on the Internet. A fuller description of these and other resources may be found in (86).

    Internet addresses
    FTP sites for the complete S. cerevisiae genome sequence (directory/yeast) (directory/pub/databases/yeast) (directory/yeast/genome-seq)
    Other S. cerevisiae data libraries
    MIPS, Martinsried, Germany (
    Sanger Center, Hinxton, UK (
    Saccharomyces Genome Database (SGD), Stanford University, USA (
    SWISS-PROT, University of Geneva, Switzerland (
    Yeast Protein Database (YPD), Proteome Inc., Beverly, MA, USA (
    GeneQuiz, European Molecular Biology Laboratory, Heidelberg, Germany (
    XREFdb, National Center for Biological Information, Baltimore, MD, USA (
    (Editor's note: For readers who would like a user-friendly guide to the yeast databases, please see the special feature at the Science Web site
  • Table 2.

    Distribution of genes and other sequence elements. Questionable proteins are defined in (2). Hypothetical proteins are the difference between all proteins predicted as ORFs and the questionable proteins. Introns include both experimentally verified examples and those predicted by the EXPLORA program. UTR, untranslated but transcribed regions.

    ElementsChromosome number
    Sequenced length (kb)2308133151,5325772701,0915634407456671,0789247841,09194812,068
    Nonsequenced identical repeats
    Name of unitENA2 and YtelCUP1rDNA and Y′
    Length of unit (kb)4 and 7<129 and 7
    Number of units2 and 2113±140 and 2
    Length of repeats (kb)8 and 14<1261,260 and 141,321
    Total length (kb)2308133151,5545772711,0915894407456672,3529247841,09194813,389
    ORFs (n)1104221728122911355722882313873345474874215694976,275
    Questionable proteins (n)33012651355712112920413023336390
    Hypothetical proteins (n)1073921607472781305152762203583145064573985664615,885
    Introns in ORFs (n)4184301351515813111719151518220
    Introns in UTR (n)020120500003020015
    Intact Ty1 (n)120610410204422433
    Intact Ty2 (n)011311100002012013
    Intact Ty3 (n)00000010100000002
    Intact Ty4 (n)00000001010000013
    Intact Ty5 (n)00100000000000001
    tRNA genes (n)2131027201036111024162221162017275
    snRNA genes (n)112120311413837240