Research NewsApoptosis

Life-Death Balance Within the Cell

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Science  01 Nov 1996:
Vol. 274, Issue 5288, pp. 724
DOI: 10.1126/science.274.5288.724


Three separate research groups report in this issue of Science (pages. 782,784, andp. 787) that a cellular protein called nuclear factor kappa B (NF-κ B)blocks the programmed form of cell suicide known as apoptosis in several cell types. This finding has led to the suggestion that blocking NF-κ B in tumor cells might make them more vulnerable to drugs or radiation.