Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma

V. Korinek, N. Barker, H. Clevers, Department of Immunology, University Hospital, Post Office Box B85500, 3508 GA Utrecht, Netherlands.
P. J. Morin and B. Vogelstein, Howard Hughes Medical Institute, Johns Hopkins Oncology Center, 424 North Bond Street, Baltimore, MD 21231, USA.
D. van Wichen and R. de Weger, Department of Pathology, University Hospital, 3508 GA Utrecht, Netherlands.
K. W. Kinzler, Johns Hopkins Oncology Center, 424 North Bond Street, Baltimore, MD 21231, USA.

↵* These authors contributed equally to this study.
↵† To whom correspondence should be addressed.

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Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC^−/− Colon Carcinoma

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