ARF1, a Transcription Factor That Binds to Auxin Response Elements

See allHide authors and affiliations

Science  20 Jun 1997:
Vol. 276, Issue 5320, pp. 1865-1868
DOI: 10.1126/science.276.5320.1865

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


The plant hormone auxin regulates plant physiology by modulating the interaction of transcription factors with auxin response elements (AuxREs) of the affected genes. A transcription factor, Auxin Response Factor 1 (ARF1), that binds to the sequence TGTCTC in AuxREs was cloned from Arabidopsis by using a yeast one-hybrid system. ARF1 has an amino-terminal DNA-binding domain related to the carboxyl terminus of the maize transactivator Viviparous-1. Sequence requirements for ARF1 binding in vitro are identical to those that confer auxin responsiveness in vivo. The carboxyl terminus of ARF1 contains two motifs found in the Aux/IAA class of proteins and appears to mediate protein-protein interactions.

  • * To whom correspondence should be addressed. E-mail: bctguilf{at}

View Full Text

Stay Connected to Science